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Alexis Vallée-Bélisle

Alexis Vallée-Bélisle

S’inspirer de la nature pour développer les nanotechnologies de demain

Faculté des arts et des sciences - Département de chimie

T. 514 343-6219

Research profile For media

The research team led by Prof. Alexis Vallée-BélisleThe has discovered how to program biomolecules or nanomachines so that they can activate at different times, acting as molecular timers. The image illustrates that time, at the molecular level, can be programmed by the very biomolecules that make up living organisms. It focuses on DNA, the biomolecule that has enabled the research group to study the biochemical mechanisms that regulate time.

Science

Tinkering with the “clockwork” mechanisms of life

19 December 2024

Press release

In addition to providing a simple design strategy to create the next generation of self-regulated nanosystems, the scientists' discoveries also shed light on how natural biomolecular assemblies may have acquired their optimal dynamics.

Science

How life appeared: rise of the nanomachines

7 February 2024

Article

The illustration depicts two chemical languages at the basis of molecular communication. The same white molecule, represented as a lock, is activated either via allostery (top) or multivalency (bottom). The allosteric activator (cyan) induces a conformational change of the lock while the multivalent activator provides the missing part of the lock, both enabling the activation by the key (pink).

Science

Decoding how molecules "talk" to each other to develop new nanotechnologies

15 August 2023

Press release

Researchers Dominic Lauzon and Alexis Vallée-Bélisle

Science

Chemists create nanomachines by breaking them apart

9 February 2023

Press release

The DNA-based nanotransporter developed by Alexis Vallée-Bélisle and his team can transport and deliver precise concentrations of drugs: in this picture, doxorubicin, a chemotherapeutic drug. These nanotransporters can also be attached to specific biomolecules to optimize drug distribution. Here, we see a nanotransporter (white) attached to albumin (pink) to maintain doxorubin (light blue) in blood circulation.

Science

DNA 'nanotransporters' to treat cancer

2 November 2022

Press release

Alexis Vallée-Bélisle

Health

A rapid and portable drug detection device using bio-nanotechnology

16 May 2022

Article

Like a two-way radio that can both receive and transmit radio waves, the fluorescent nanoantenna designed by Alexis Vallée-Bélisle and his team receives light in one colour and depending on the protein movement it senses, then transmits light back in another colour, which we can detect. One of the main innovations of these nanoantennas is that the receiver part of the antenna (bright green) is also employed to sense the molecular surface of the protein studied via molecular interaction.

Health

Chemists use DNA to build the world’s tiniest antenna

10 January 2022

Press release

Vincent De Guire, Nancy Schoenbrunner and Alexis Vallée-Bélisle, three of the five co-founders of Anasens

Health

Anasens: a UdeM start-up with a bright future!

19 May 2021

Article

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In the media (fr)