Discrimination damages the body — and makes you age faster

In 5 seconds Researchers at UdeM find that the lifelong stress of feeling singled out has a direct effect on the physical health of sexually and gender-diverse people.
According to Juster, the research is the first to distinguish gender identity, sexual orientation and biological sex as three independent dimensions for assessing allostatic load.

Have you always been discriminated against as an LGBTQ+ person? Has it been so bad, and the stress so heavy, you literally feel it in your bones? Well, it turns out that's exactly what happens: discrimination damages the body and brain.

That's the conclusion of a new study by researchers at Université de Montréal, who found that discrimination against sexually and gender-diverse people leaves measurable biological traces in the body — so much so, it should be considered a chronic health burden.

Published in Psychoneuroendocrinology, the study was done on 357 Montreal adults aged 18 to 79: they included 129 cisgender sexual minority men and women, 96 transgender and non-binary people, and 72 cisgender heterosexual men and women.

 

Measuring allostatic load

In the UdeM Centre for Studies on Sex*Gender, Allostasis, and Resilience, run by psychiatry professor Robert-Paul Juster, researchers measured the participants' allostatic load, the cumulative biological wear-and-tear associated with chronic stress.

To do so, they looked at 16 biomarkers affecting the subjects' cardiovascular, metabolic, neuroendocrine and immune systems. 

Divided into seven subgroups based on their gender identity and sexual orientation, the participants also completed questionnaires about their experiences of discrimination and their health behaviours.

"Our results show that, after controlling for age, major life experiences of discrimination and daily microaggressions were positively associated with allostatic load," said Nevena Chuntova, the study's lead author.

"This means that these two types of discriminatory events independently contribute to physiological dysregulation, creating a cumulative health burden and accelerated aging," said Chuntova, a doctoral student in psychology at UdeM.

High levels on the male side

The study revealed significant disparities: people on the male spectrum (cisgender and transgender men) had the highest levels of allostatic load, while sexual minority men (bisexual and gay) also showed high levels of biological stress.

“Gender identity and sexual orientation both significantly predicted allostatic load, with people on the male spectrum and sexual minority men showing the highest levels,” said Chuntova.

These findings provide empirical support demonstrating that discrimination can exert direct biological effects through stress systems, she added. 

"Contrary to the commonly held belief that discrimination affects health mainly through the adoption of risky behaviours — smoking, being sedentary, using alcohol and drugs — this study reveals a direct link between discrimination and physiological disruption," Chuntova said. 

 

Stigma ‘gets under the skin’

“Chronic discrimination seems to directly disrupts a person's biological systems, acting as a stressor that gets under their skin, regardless of any change in behaviour," Chuntova said.

The data "clearly show that discrimination is not just a matter of social justice—it is a public health issue with measurable biological consequences," she added.

The research is unique, said Juster, the senior author leading the research.

“Ours is the first to distinguish gender identity, sexual orientation and biological sex as three independent dimensions for assessing allostatic load,” he said.

“It's an important scientific discovery that validates the experiences of 2S/LGBTQIA+ individuals. It shows that the impact of stigma on their health is a stress that literally becomes embedded in their body.”

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